Tretinoin 0.1% Cream

Tretinoin is widely regarded as the gold standard topical prescription treatment for improving skin quality and reducing the visible signs of ageing.

By increasing skin cell turnover and stimulating collagen production, tretinoin helps improve:

• Fine lines and wrinkles
• Sun damage
• Uneven skin tone
• Pigmentation
• Acne
• Post-inflammatory pigmentation
• Skin texture
• Enlarged pores

The 0.1% strength is the strongest commonly prescribed formulation and is generally suitable for patients who have already built tolerance to lower strengths or where clinically appropriate following assessment by one of our prescribers.

How it works

Tretinoin binds to receptors within the skin to:

• Increase collagen production
• Reduce collagen breakdown
• Speed up skin renewal
• Improve epidermal thickness
• Reduce blocked pores
• Improve overall skin quality

Unlike cosmetic retinol products, tretinoin is the active form of vitamin A and does not require conversion by the skin, making it significantly more effective.

Benefits

✔ Prescription-strength anti-ageing treatment

✔ Softens fine lines

✔ Improves wrinkles

✔ Brightens dull skin

✔ Improves pigmentation

✔ Helps reduce acne

✔ Refines pores

✔ Improves skin texture

✔ Encourages collagen production

✔ Long-term improvement in skin quality

Who is it suitable for?

Suitable for adults wishing to treat:

• Ageing skin
• Acne
• Pigmentation
• Sun damage
• Uneven skin tone
• Rough skin texture

Not suitable during pregnancy or breastfeeding.

How to use

Unless advised otherwise by your prescriber:

Evening only.

Apply a pea-sized amount to the entire face.

Avoid:

• Eyes
• Eyelids
• Lips
• Corners of the nose

Start slowly:

Weeks 1–2:
Use twice weekly.

Weeks 3–4:
Use every other night if tolerated.

Thereafter:
Increase to nightly use if your skin is comfortable.

Always apply moisturiser afterwards.

Use SPF 30–50 every morning.

Possible side effects

During the first few weeks it is common to experience:

• Dryness
• Redness
• Mild peeling
• Temporary irritation
• Increased sensitivity

These effects usually improve as the skin adapts.

Important information

Do not use if:

• Pregnant
• Planning pregnancy
• Breastfeeding
• Allergic to tretinoin

Avoid:

• Waxing treated skin
• Harsh scrubs
• Strong acids unless advised
• Excessive sun exposure

Daily sunscreen is essential.

Medical Consultation

This medication requires completion of a medical questionnaire.

One of our UK prescribers will review your answers before treatment is approved.

If suitable, your prescription will be issued and dispensed by our licensed pharmacy partner.

If unsuitable, you will not be charged for the medication and we will advise on alternative treatment options where appropriate.

Ingredients

Active ingredient:

Tretinoin 0.1%

Other ingredients vary depending on manufacturer.